The DIDB® is a very friendly, easy to use and up-to-date database to retrieve in a couple of clicks, key and relevant information on drug-drug Interactions. The use of DIDB® is clearly a time saver in our day- to-day work.
Quantitative Clinical Pharmacology
Large Pharmaceutical/Biotech, Belgium
I have been using DIDB® since the very beginning. I am very pleased to see its growth in the past 20 years with continuous improvements, expanding from a database focusing on enzyme-based DDIs to include transporters, special populations, pharmacogenetics, clinical tools, food effect studies, drug formulations, and many more. DIDB® helps me gain access to valuable mechanistic and clinical information in an organized and systemic manner.
Deputy Director
Government agency, USA
The DIDB® is a powerful tool, to obtain in vitro metabolism/transporter and in vivo clinical PK data, to facilitate decision making, and to inform preclinical and clinical pharmacology study design. DIDB® increases my productivity and allows me greater insight to assess potential DDIs and pharmacogenomic interactions.
Senior Director
Small-size Pharmaceutical/Biotech, USA
The DIDB® has been extremely beneficial for data collection. For example, there is access to extensive datasets describing known CYP inhibitors/inducers and substrates, with references to studies that have in-depth citation summaries. This has enabled rapid collection of key pharmacokinetic data, along with study parameters, such as population phenotypes, genotypes, and sample sizes.
Director
Pharmaceutical/Biotech, UK
As a Senior Clinical Pharmacologist with a deep DDI interest and mechanistic approach, I use the database extensively to inform protocols, drug development strategies, study designs, and labelling work etc.
I can’t imagine to do my work without it.
Senior Director
Biosimulation Service Provider, Sweden
The DIDB® is an amazing resource. It streamlines our research of pharmacokinetic parameters for individual drugs and has cut down our time to evaluate a medication by at least 50%. The team there is responsive to questions, and they have a nice training program to orient you to the tool. The ability to filter drug data in a seemingly infinite number of ways is a key feature.
Senior Vice President of Medical Affairs
Pharmacogenetics & Personalized Medicine Service Provider, USA
We are using online searches in DIDB® for robust planning and upfront modelling of in vitro experiments (e.g., for optimizing choices of DME phenotyping inhibitors). The fast and sophisticated access to the complete in vitro dataset, available from the scientific community, facilitates the design of such in vitro studies tremendously.
Associate Director, Senior DMPK Expert
Preclinical Service Provider, Germany
The DIDB® tool has always been very good, and I have used it for a number of years. It has become a routine part of my workflow. The Excel sheet pull downs and literature cross-referencing function is extremely useful. I have used the sheets in many of my publications and slide decks.
It is where I go first for drug interaction searches.
Senior Scientific Director
Large Pharmaceutical/Biotech, USA
The DIDB® is a precious tool for clinical pharmacologists; it is of invaluable help for drug-drug interactions, but there is much more, with all the available resources, monographs, and information on PK, effects of hepatic and renal impairment, side and pharmacodynamic effects.
Senior Director
Biosimulation Service Provider, Italy
DIDB® is a powerful resource. It has relevant and up-to-date ADME data both in vitro and clinical.
Senior Director
Large Pharmaceutical/Biotech, USA