Archives: FAQs

In vitro, different extracts (e.g., aqueous, ethanol, methanol, etc.) of a natural product (NP) may be studied. To be sure to retrieve all in vitro results related to a given NP, users need to include these extracts in the query in addition to the NP itself and the various ingredients. 

A quick way to find all the relevant in vitro and/or in vivo data involving food products is to use the following queries: Basic Queries > Therapeutic Class Queries > One Therapeutic Class, type or select “Food Products” from the drop-down list in the Therapeutic Class area, and select between Objects or Precipitants and in vitro and/or in vivo. In specific, the “Therapeutic Class (Advanced)” query on the same page can be used to search data with a focus on a specific mechanism.

The majority of biologics curated in DIDB belong to two therapeutic classes: immunomodulators biologics and neoplastic biologics. To retrieve data involving biologics belonging to these two therapeutic classes use the following query: Basic Queries > Therapeutic Class Queries > One Therapeutic Class and type in one of the therapeutic classes, select between objects or precipitants and “in vitro” and/or “in vivo”. Perform the same search for the other therapeutic class.

To find all biologics included in DIDB, go to Monographs > PK profiles. In the table review results select “yes” in the column of “Biologics”. Then you can use the DIDB queries to find data for any biologics included in this table but not belonging to the above therapeutic classes.

Additionally, you can use the full text search function on the DIDB homepage by typing in “biologics” to do a broad search from citations, monographs, and resources.

If you are interested in the newly approved biologics, you can access all data extracted from BLA reviews